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Chantix, one of the most widely used prescription drugs for smoking cessation, comes with such serious side effects that drug safety advocate Kim Witczak fought the removal of its "black box" warning about the risk of suicidal thoughts, violence and aggression.

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Multivariate logistic models showed that urbanization (adjusted odds ratio (AOR) = 1.2) and having a history of systemic disease, including rheumatic disease (AOR = 2.1), genital aphthous disease (AOR = 11.7), depression (AOR = 1.3), chronic headaches (AOR = 1.8), diabetes mellitus (AOR = 1.6), and epilepsy (AOR = 2), were independent predictors of RAS

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